Sanesco Health > Tranquilent - 30 Tablets PATIENT ONLY

A unique, chewable, cherry and raspberry-flavored formula providing support for the inhibitory neurotransmitter system—both serotonergic and GABAergic neurotransmission. May be used when calm or relaxation is needed in the short term as well as for rebalancing the inhibitory system over the long term.

Balance between inhibitory and excitatory neurotransmitter activity is vital to health and well-being. Inhibitory neurotransmitters such as serotonin and GABA maintain excitatory signals in the nervous system. That’s why supporting inhibitory neurotransmitters often results in a balanced calming and relaxing effect. 

Tranquilent includes ingredients that support the optimal function of inhibitory neurotransmitter activity.* 5-HTP is a precursor that supports serotonin synthesis.* Myo-inositol works to support healthy serotonergic receptors.¹ Theanine, as Suntheanine®, intake has been shown to increase GABA activity and function.

L-theanine as Suntheanine® (standardized to >99%): L-Theanine intake is shown to restore balanced relaxation by balancing multiple internal mechanisms, leading to increased healthy GABA activity while antagonizing glutamate receptors to support balance and decreased norepinephrine activity.*^2,3

5-HTP: A naturally occurring amino acid and metabolite of L–tryptophan. 5-HTP is the direct precursor in the biosynthesis of serotonin.* Use of 5-HTP avoids the rate-limiting conversion of tryptophan to 5-HTP. 

Myo-inositol (inositol) A precursor for the second messenger system (phosphatidyl-inositol) used by noradrenergic, cholinergic and serotonergic receptors.* Inositol regulates numerous healthy cellular functions including optimal membrane and receptor function*¹

1. Colodny L and Hoffman RL. Altern Med Rev. 1998;3(6):432-447. 
2. Nathan PJ, et al. 2006. J Herb Pharmacother. 6:21–30.
3. Kimura and Morata. Chem Parhm Bull (Tokyo). 1986. Jul; 34 (7) 3053.7.
4. Ngo D and Vo TS. Molecules. 2019;24(15):2678. 
5. Longone P, et al. Frontiers in endocrinology. (2011):2. 
6. Møller SE. (1992). Serotonin, carbohydrates, and atypical depression. Pharmacol Toxicol. 71 Suppl 1:61-71. Slide 19,20 
7. Wurtman J and Wurtman R. Curr Obes. Rep. 2018 Mar;7(1):1-5.
8. Ho KY, et al. Br J Anaesth. 2010 Setp;105(3):371-6.
9. Hull EM, et al. Physiology and Behavior. 2004 Nov;83(2):291-307.
10. Crowell MD. Br J Pharmacol. 2004 Apr;141(8):1285-93.
11. Rybaczy LA, et al. BMC Women’s Health. 2005. 
12. Yonkers KA, et al. ancet. 2008 Apr 5;371(9619):1200-1210.
13. Bravo R, et. al. Age (Dordr). 2013 Aug;35(4):1277-86.
14. Tauscher J, et al. The Amer J of Psychiatry. 2001 Aug 1;158(8):1326-1328.

Supplement Facts

Serving Size: 1 Chewable Tablet
Servings per Container: 30 Tablets

Tranquilent™ Formula  1,045mg  
Myo-inositol (inositol)
L-Theanine (as Suntheanine®)
5-hydroxytryptophan (Griffonia simplicifolia) (seed)

Recommended Dose: Chew one (1) tablet daily or as directed by your clinician.